Wonderful New Resource Now Online!

I thought I would pass this along to anyone as interested in genetics/genomics as I am. A new anatomy and genetics atlas of the brain has been brought online, allowing users to visualize activity for any gene they wish across all regions of the brain. This is especially useful when exploring what effects a given defect or mutation might have in neurologic function.

Mouse and Human Brain Maps

Just as a quick example, here's the brain expression profile for a gene I helped sequence in mice a few years ago:

Human activity of CDKN1B/p27 - You can see from the microarray data that it's highly active in the limbic lobe (LL), and almost entirely inactive in the cerebellum.

You can also see a more anatomically representative view of this data by using the "Mouse Brain" link on the front page. The image I've linked to is using the same gene (cdkn1b/p27) and is a coronal slice through a more posterior portion of the brain. You can see, the very dark purple staining region near the center of the brain (the limbic lobes) show a high level of activity, with the rest of the brain showing relatively little, which is exactly what the human brain data showed in the first link.

Sorry if this isn't as interesting to others as it is to me...I just think this is an absolutely wonderful resource, both for furthering intricate genetic research, as well as helping the general public understand the interplay between genetics and overall body functioning.

I bet the Germans back in the 30's - 40's would have loved it.

It looks like a good resource but thats a little advanced for me.

Good post though.

reply to post by SWCCFAN


Why would the Germans have loved it? Have you forgotten that the Germans learned about eugenics from your countrymen, the Americans?

Anyways, that's beside the point. This resource isn't really useful in a eugenics sense, as it shows how LITTLE genetic variation there is in individuals, not the opposite.

lol dude doesn't realize your more then likely Germain descent.
Of course I may be wrong but your screen name sure seams to have a Germain influence.
anyway so you mapped a mouse brain I immange he was mostly thinking of cheese and tom dude if your the real thing this is wayyyy beyond me

reply to post by xxcalbier


Close (well, not really =P). I'm Russian, though I'm an American citizen, now.