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Officials from the National Accountability Bureau asked for permission to arrest the minister in charge of law and order and the war on terror within Pakistan.
The move followed a supreme court ruling earlier this week which overturned an amnesty introduced by former president General Musharraf to bring back the late former prime minister Benazir Bhutto and her senior aides from exile in 2007.
On Thursday, the defence minister, Ahmed Mukhtar was physically prevented from boarding a flight for an official visit to China. The two ministers are key contacts for Western allies for Pakistan's role in the anti-terror fight.