Antidepressants not more useful than placebo-drugs in most cases

Antidepressants not more useful than placebo-drugs in most cases

medicine.plosjournals.org

Drug–placebo differences in antidepressant efficacy increase as a function of baseline severity, but are relatively small even for severely depressed patients. The relationship between initial severity and antidepressant efficacy is attributable to decreased responsiveness to placebo among very severely depressed patients, rather than to increased responsiveness to medication.

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medicine.plosjournals.org
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