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By Will Dunham
WASHINGTON (Reuters) - Scientists have known for seven decades that mice, dogs, fruit flies and other animals given diets bordering on starvation tended to live up to 40 percent longer than their better-fed cousins.
Now they think they know why.
They identified a gene in roundworms on Wednesday that directly links calorie restriction to longer lifespan.
The researchers, led by Andrew Dillin of the Salk Institute for Biological Studies in La Jolla, California, said a gene called pha-4 plays a role in gut development in embryonic worms but in adults is associated with calorie-restricted longevity.