a reply to:
ketsuko
If you or anyone else is interested and unfamiliar with Nextstrain they are an amazingong resource on sarscov2 mutations and have been
tracing/following the phylogeny simce very early on. Originally designed for other viruses (which are also available at the link below) they quickly
realized the significance of this virus and began analyzing and documenting thw results publicly.
Like most of us 'common folk' a lot of the more scientific data on virology is compiled in such a way that reading through documents mine as well be
sumerian hieroglyphs To me lol however one thing i really appreciated , and the reason i try to share the link so often, is that the interface used by
Nextstrain allows it to be viewed in several different visual formats. (charts/graphs/etc.) Which in my opinon helps a LOT on grasping specifically
the amount of mutations already documented, where they are/ came from, and even allows the user to view individual areas or countries not just the
overall phylogeny.
In laymens terms, think 'Ancestry DNA' or a geneology chart only instead of our ancestors its rhe virus and its 'ancestors'/ mutations and predecessor
mutations.
I know it can be hard for some people to really grasp the sheer number of mutations already seen just hy reading the info- but , imo at least, seeing
it laid out in a color coded chart (s) really helps put it into am easy to umderstand format. It also has a wealth of other information that i
personaly have no clue about lol
main NextStrain page for SARScov2
To see the interactive global map
Global NextStrain Data Graph
Basically from left to right shows the mutations currently knowm ane documented globally. Left side being 'older' or earliest identified, and as one
moves to the righthand side each individual branch would be a major mutation, followed by the mutations from that mutation, etc. Etc.
You can also use the map at the bottom to 'zoom' in on a particular country or area and see the information available for just that region.
The good news with all of that is that even though Coronaviruses in general are known to rapidly mutate as a whole, SARScov2 thusfar has shown to be
relatively Stable even after mutations. Basically even though it is mutating, as expected, the changes within the genome are mostly to areas that dont
actusllt effect the way the virus is transmitted or behaves in the body thankfully. However that cant be said for 100% of them , which is where the
variants of concern come from usually referenced. Those variants have mutated in areas that do (or may/believed to) affect the way the virus behaves.
Nextstrain also has been at the forefront of both identifying aswell as tracking those speciric variants as well. That can be found at
Covariant page
And just fwiw to anyone else who enjoys following the Science directly instead of what eventually makes it to the news, Emma Hodcroft who is one of
the lead scientist working with Nextstrain is present on Twitter and in my experience is actually really helpful resource both to interact and ask
questions to aswell as just to follow the info she posts. I believe she is from Europe so a lot of her info relates specifically there. For those in
the U.S Trevor Bedford is also on Twitter and is based on the west coast and has been ahead of the game in modeling and tracking whats going on here.
Imo of course. He is the reason i even knew about Dr Hellen Cho in Seattle who defied the trump administrations orders to not test patients she
suspected of having covid very early on, and thanks to her tenacity the only reason we know for sure that by January 21st of last year we already were
seeing community spread within the U.S border.... Right before we stopped testing all together for over a month leading up to the inital outbreak here
in the states. Im kinda going off topic now lol but using the data at the time Trevor Bedford has been ahead of the curve and instrumental , imo, in
tracking the spread of the virus as well as the variants that have popped up along the way. Not to mention , providing actual data and info in am easy
to understand wAy for those of us who may have the interest but didnt spend years in school learning about all the intricacies of virology and
epidemiology.
Apologies for the long reply- im really bad at short comments lol but because the subject of the post is aboit the mutations Nextstrain was the first
thing that came to mind and figured id offer the info incase anyone else either didnt know about it or was just curious to look over it themselves.
edit on 303026003pm30America/Chicagov by itswhatev because: Sigh, typos.